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Cardiac surgery post-op patients may benefit from statin therapy, which researchers have found to reduce overall recovery time, particularly for patients with a tendency toward wound-healing complications. Statins’ effect on the body’s inflammatory response likely explains the shortened healing time. But analysis has indicated that some statins are better than others in this respect.
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— Barbara Worthington, editor |
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Statins May Improve Wound Healing Following Cardiac Surgery
Statin therapy may help to improve wound healing in patients following cardiac surgery and reduce overall recovery time, especially in patients who are prone to healing complications, according to a review article in the August issue of The Annals of Thoracic Surgery.
“Statins have become one of the most widely prescribed medications in the world. While they are typically used to manage high cholesterol levels, a number of researchers have been investigating the benefits of statins in other conditions, such as severe infections or following organ transplantation,” says lead author Gerard J. Fitzmaurice, MRCSI, MSc, from Our Lady’s Children’s Hospital in Dublin, Ireland.
Fitzmaurice and colleagues reviewed existing literature, most of which included laboratory-based studies on animals, and found that statins appear to affect the inflammatory response, thereby reducing the length of time needed to heal following surgery (13.0 days vs. 18.7 days) and potentially resulting in smaller scars.
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SenMoCOR
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