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According to research published in Diabetes Care, when metformin fails to control disease in patients with type 2 diabetes, a combination of two drugs—dapagliflozin and exenatide—may provide better glycemic control than does either drug alone. Moreover, according to the multicenter double-blind, phase 3, randomized control trial, the benefit extends for more than two years.
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— Kate Jackson, editor |
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Combo Drug Treatment for Diabetes
Patients with type 2 diabetes often take metformin as first-line therapy to help stabilize their blood glucose. Eventually, some patients no longer respond to metformin and require additional treatment. A few years ago, pivotal short-term trials showed that a combination of two drugs controlled diabetes progression better than either single drug alone. Now, new research demonstrates that this drug combo of dapagliflozin and exenatide continues to stay effective, without loss of effect, after two years of continual use.
“Many therapies in diabetes management are short-lived, which is why it’s useful to test for long-term effect,” says senior author Serge Jabbour, MD, director of the division of endocrinology and the Diabetes Center at Thomas Jefferson University in Philadelphia. “Our study showed that a combo regimen of dapagliflozin and exenatide continued to control patients’ glucose for over two years. This is very encouraging.”
The results of this multicenter double-blind, phase 3, randomized controlled trial were recently published in the journal Diabetes Care.
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Tramadol and Hip Fracture
This widely prescribed drug may be more risky than many realize. Read more »
Sarcopenia & Diabetes
Muscle loss is a significant quality-of-life issue for patients with diabetes. Read more »
The ABCs of Telehealth for Mental Health
During the coronavirus pandemic, teletherapy has become a vital support system. Read more » |
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A Shoe Insole Designed for Older Adults
The SelectFlex arch control insole from Alliance Design & Development Group is an advanced orthotic that lets users adjust levels of arch support. It helps older adults alleviate and perhaps prevent foot pain through its Variable Resistance Beam adjustable suspension and joint support technology. Learn more »
Projective Noncompression Sleeves
Two new styles of Limbkeepers’ noncompression knit sleeves and gloves are available to help older adults protect their fragile skin. The new elbow and full fit arm sleeves, available in sizes to comfortably accommodate all arm sizes, protect against chafing that occurs with use and the skin damage that can occur during the activity of daily living. Learn more » |
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A resource for professionals looking for new opportunities, as well as those physicians just curious to see what's out there, our Physician Recruitment Center gives physician recruiters a powerful tool to fill partnership opportunities, academic appointments, and hospital staff positions. To support your product marketing or recruiting needs, e-mail our experienced account executives today at sales@gvpub.com for more information or call 800-278-4400! |
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There’s No Age Limit for Therapy
Older adults have been no more strangers to mental health issues than are younger people, and now, during the pandemic, there’s been an increase in loneliness and grief disorders and an amplification of preexisting concerns. The New York Times reports that while older adults are often reluctant to avail themselves of therapy, largely due to a lingering stigma, they may benefit from talking to a therapist, but access is often a challenge.
Brain Fog After COVID-19
After being critically ill from COVID-19, many older adults are experiencing sudden cognitive dysfunction. Zijian Chen, MD, medical director of the Center for Post-COVID Care at Mount Sinai Health System in New York says they’re describing memory disturbances, difficulty concentrating, and an inability to gather their thoughts—these on top of the other physical sequelae of the illness, The Philadelphia Inquirer reports.
COVID’s Effect on the Brain
Another finding related to cognitive abilities among older adults who’ve had COVID-19, according to a questionnaire surveying 84,000 people in the United Kingdom, is that the brains of some who had or suspected they were infected by the virus appear to have aged by about 10 years, Newsweek reports. While the research was not peer reviewed, it suggests an area of concern and indicated a need for further research.
Positive Aging
Can a positive attitude be an inoculation against memory loss? Research published in Psychological Science suggests that those who have “positive affect”—feelings of cheerfulness and enthusiasm—may experience less memory loss as they age than others without such a temperament, ScienceDaily reports. |
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