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Editor's E-Note
An approach to treating depression is never one-size-fits-all, but that’s particularly true when it comes to patients with Alzheimer’s, in whom antidepressants are often ineffective. A study led by University of Bristol researchers demonstrates that risk factors are different in patients with Alzheimer’s, supporting the notion that there may be a different underlying cause for depression in such individuals.
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— Kate Jackson, editor |
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Depression in Alzheimer's Has Different Risk Factors to Depression in Those Without Dementia
Depression in Alzheimer's has different risk factors than depression in older adults without the disease, finds a major new study in the Journal of Alzheimer’s Disease. The University of Bristol–led research looked at over 2,000 people with the disease to explain why current antidepressants are ineffective for people living with depression in Alzheimer’s.
Depression in dementia is common. Up to 16% of people with Alzheimer’s disease develop depression, but it is not known why it is more common in those living with Alzheimer’s than in older adults without dementia. Individuals with depression in dementia also appear to have different symptomatology with fewer symptoms of appetite reduction and thoughts of life not being worth living. Currently available antidepressants are ineffective, making the depression difficult to treat.
Alzheimer’s disease is a physical disease that affects the brain and, according to the charity Alzheimer’s Society, which cofunded the research, 900,000 people in the United Kingdom have a form of dementia.
Researchers from Bristol’s Dementia Research Group wanted to investigate whether risk factors known to increase the risk of depression in adults without dementia also increased the risk of depression in those with Alzheimer's to identify possible new treatment targets.
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Home Health Aides Don’t Get Their Due
Despite being in high demand, home health workers get little respect. Stat News reports on the toll their jobs take on these undervalued members of the health care work force.
Assessing and Diagnosing Heart Health With Artificial Intelligence
Sonographers come in second to artificial intelligence technology when it comes to assessing and diagnosing heart health. Science Daily reports on the innovative research by investigators from the Smidt Heart Institute and the Division of Artificial Intelligence in Medicine at Cedars-Sinai.
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The Pacemaker of the Future?
According to researchers at Northwestern University in Chicago, a graphene tattoo, developed by a University of Texas at Austin biomedical engineer, Dmitry Kireev, may transmit electrical signals that keep the heart beating properly. Science News reports on the research.
Slowing the Biological Clock
University of California, San Diego researchers are exploring how rewiring genetic circuitry might delay aging and extend the lifespan. Newsweek reports on their study, published in Science. |
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A Perspective on an Integrated Care Model
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